Gallamine
Gallamine
Gallamine (pronounced: /ɡæləmiːn/) is a non-depolarizing muscle relaxant. It was first synthesized in the 1940s and is also known by its trade name, Flaxedil.
Etymology
The term "Gallamine" is derived from the name of its discoverer, the British pharmacologist James W. Black. It was named in honor of his alma mater, the University of Glasgow.
Usage
Gallamine is used primarily in anesthesia to facilitate tracheal intubation, and to provide skeletal muscle relaxation during surgery or mechanical ventilation. It works by blocking the effects of acetylcholine at the motor end-plate of the neuromuscular junction.
Pharmacology
Gallamine is a synthetic triethiodide that acts as a non-depolarizing neuromuscular blocking agent. It competes with acetylcholine for binding sites on the motor end-plate, thereby inhibiting the action of acetylcholine and causing muscle relaxation.
Related Terms
See Also
External links
- Medical encyclopedia article on Gallamine
- Wikipedia's article - Gallamine
This WikiMD dictionary article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski