Galanin

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Galanin

Galanin (pronounced: ga-lan-in) is a neuropeptide that is widely distributed throughout the nervous system and the endocrine system. It is involved in a variety of physiological functions, including pain modulation, learning and memory, feeding behavior, and mood regulation.

Etymology

The term "Galanin" is derived from the first few amino acids in its sequence: galycine, alanine, and aninine.

Function

Galanin is a 29-amino acid peptide that is synthesized and released by neurons. It acts as a neurotransmitter or neuromodulator, binding to specific receptors on the surface of cells to influence their activity. There are three known types of galanin receptors: GalR1, GalR2, and GalR3.

Clinical significance

Galanin has been implicated in a number of medical conditions, including Alzheimer's disease, depression, anxiety, epilepsy, and chronic pain. It is also involved in the regulation of appetite and body weight, and may play a role in obesity and eating disorders.

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