Fructose

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Fructose

Fructose (/ˈfrʌktəʊs/), also known as fruit sugar, is a simple ketonic monosaccharide found in many plants, where it is often bonded to glucose to form the disaccharide sucrose.

Etymology

The word "fructose" was coined in 1857 from the Latin for fructus (fruit) and the generic chemical suffix for sugars, '-ose'.

Structure and Bonding

Fructose is a 6-carbon polyhydroxyketone. It is an isomer of glucose, which means they have the same molecular formula (C6H12O6) but different structural arrangements.

Metabolism

Fructose is metabolized in the liver, where it is converted into fructose-1-phosphate by the action of fructokinase. Subsequent steps in the metabolic pathway convert fructose to glyceraldehyde and dihydroxyacetone phosphate.

Health Effects

Excessive consumption of fructose (particularly in the form of high-fructose corn syrup) has been linked to increased risk of obesity, diabetes, and non-alcoholic fatty liver disease.

Related Terms

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