Friability
Friability
Friability (pronounced: /fraɪəˈbɪlɪti/) is a term used in pharmacology and material science to describe the physical property of a solid substance to be easily crumbled or pulverized.
Etymology
The term "friability" is derived from the Latin word "friabilis", which means "easily crumbled".
Definition
In pharmacology, friability is a test used to determine the physical strength of a tablet. The test is carried out by tumbling the tablets and then determining the percentage of weight loss. The United States Pharmacopeia (USP) states that tablets should not lose more than 1% of their weight in this test.
In material science, friability refers to the tendency of a material to break, crumble, or degrade under pressure or impact. This property is often used to assess the durability of materials, such as concrete or ceramics.
Related Terms
- Abrasion: The process of scraping or wearing away, often discussed in relation to friability.
- Compressibility: The property of being able to compact a substance, often inversely related to friability.
- Hardness: A measure of resistance to deformation, often inversely related to friability.
- Pharmaceutical formulation: The process in which different chemical substances are combined to produce a final medicinal product, often considering the friability of the product.
See Also
External links
- Medical encyclopedia article on Friability
- Wikipedia's article - Friability
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