Free fatty acids

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Free Fatty Acids

Free fatty acids (FFA), also known as non-esterified fatty acids (NEFA), are a type of lipid that circulates in the bloodstream. They are a major source of energy for the body and are involved in various biochemical processes.

Pronunciation

Free fatty acids: /fri: 'fæti 'æsɪdz/

Etymology

The term "free fatty acids" is derived from the fact that these molecules are not attached to other molecules and are thus "free". The term "fatty acid" comes from the fact that these molecules are made up of a carboxylic acid group attached to a long hydrocarbon chain, which is typically rich in hydrogen and carbon atoms, giving it a "fatty" or oily nature.

Related Terms

  • Lipid: A group of naturally occurring molecules that include fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E, and K), monoglycerides, diglycerides, triglycerides, and phospholipids.
  • Carboxylic acid: An organic compound that contains a carboxyl group (C(=O)OH).
  • Hydrocarbon: Compounds consisting entirely of hydrogen and carbon.
  • Biochemical: Relating to biochemistry, the application of the tools and concepts of chemistry to living systems.

Functions

Free fatty acids are a crucial source of energy for the body. They are released from adipose tissue and transported to other tissues for oxidation and energy production. In addition to their role in energy metabolism, free fatty acids also play a role in cell signaling and inflammation.

Health Implications

Elevated levels of free fatty acids in the blood can lead to various health problems, including insulin resistance, type 2 diabetes, and cardiovascular disease. Therefore, maintaining a healthy balance of free fatty acids is important for overall health.

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