Framingham Heart Study

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Framingham Heart Study

The Framingham Heart Study (pronounced: fra-ming-ham hahrt stuhd-ee) is a long-term, ongoing cardiovascular study on residents of the town of Framingham, Massachusetts. The study began in 1948 with 5,209 adult subjects from Framingham, and is now on its third generation of participants.

Etymology

The study is named after the town of Framingham, Massachusetts, where the study is based.

Overview

The Framingham Heart Study is a project of the National Heart, Lung, and Blood Institute and Boston University. The objective of the study is to identify the common factors or characteristics that contribute to cardiovascular disease by following its development over a long period in a large group of participants who had not yet developed overt symptoms of cardiovascular disease or suffered a heart attack or stroke.

Findings

The Framingham Heart Study has led to the identification of major cardiovascular risk factors, such as high blood pressure, high blood cholesterol, smoking, obesity, diabetes, and physical inactivity – as well as a great deal of valuable information on the effects of related factors such as blood triglyceride and HDL cholesterol levels, age, gender, and psychosocial issues.

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