Fosaprepitant
Fosaprepitant
Fosaprepitant (pronounced foh-sa-PREP-i-tant) is a medication used in the prevention of chemotherapy-induced nausea and vomiting. It is a member of the neurokinin 1 (NK1) receptor antagonists class of drugs.
Etymology
The name "Fosaprepitant" is derived from its chemical structure. "Fos" refers to the phosphate group in its structure, "aprepitant" is the name of the active metabolite.
Pharmacology
Fosaprepitant is a prodrug of aprepitant, meaning it is metabolized in the body to become the active drug aprepitant. It works by blocking the action of substance P, a neurotransmitter in the brain that plays a key role in triggering nausea and vomiting.
Usage
Fosaprepitant is used in combination with other medications to prevent nausea and vomiting caused by chemotherapy. It is usually given before chemotherapy and works by blocking the action of substance P in the brain, which helps to reduce these side effects.
Related Terms
External links
- Medical encyclopedia article on Fosaprepitant
- Wikipedia's article - Fosaprepitant
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