File:Monoclonal antibodies used in the treatment of non small cell lung cancer and their mechanism of action.webp

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Monoclonal_antibodies_used_in_the_treatment_of_non_small_cell_lung_cancer_and_their_mechanism_of_action.webp ‎(550 × 354 pixels, file size: 23 KB, MIME type: image/webp)

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Description
English: Non-small cell lung cancer (NSCLC) cells expressing programmed death-ligand 1 (PD-L1) could interact with programmed death receptor 1 (PD-1) expressed on the surface of T cells, and result in decreased tumor cell kill by the immune system. Atezolizumab is an anti PD-L1 monoclonal antibody. Nivolumab and Pembrolizumab are anti PD-1 monoclonal antibodies. Ipilimumab is a monoclonal antibody that targets Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) on the surface of T cells. Bevacizumab is a monoclonal antibody that targets Vascular Endothelial Growth Factor (VEGF) in the circulation and functions as an angiogenesis inhibitor. First line Immunotherapy for Non-Small Cell Lung Cancer. Nasser NJ, Gorenberg M, Agbarya A. Pharmaceuticals (Basel). 2020 Nov 8;13(11):373. https://doi.org/10.3390/ph13110373
Date
Source

First line Immunotherapy for Non-Small Cell Lung Cancer. Nasser NJ, Gorenberg M, Agbarya A. Pharmaceuticals (Basel). 2020 Nov 8;13(11):373.

https://doi.org/10.3390/ph13110373
Author

First line Immunotherapy for Non-Small Cell Lung Cancer. Nasser NJ, Gorenberg M, Agbarya A.

Pharmaceuticals (Basel). 2020 Nov 8;13(11):373. doi: 10.3390/ph13110373.

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Monoclonal antibodies used in the treatment of non small cell lung cancer and their mechanism of action. https://doi.org/10.3390/ph13110373

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current04:17, 10 December 2020Thumbnail for version as of 04:17, 10 December 2020550 × 354 (23 KB)wikimediacommons>SannecolaUploaded a work by First line Immunotherapy for Non-Small Cell Lung Cancer. Nasser NJ, Gorenberg M, Agbarya A. Pharmaceuticals (Basel). 2020 Nov 8;13(11):373. doi: 10.3390/ph13110373. from First line Immunotherapy for Non-Small Cell Lung Cancer. Nasser NJ, Gorenberg M, Agbarya A. Pharmaceuticals (Basel). 2020 Nov 8;13(11):373. https://doi.org/10.3390/ph13110373 with UploadWizard

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