Fick principle
Fick Principle
Fick Principle (pronunciation: /fɪk/), named after the German physiologist Adolf Fick, is a foundational concept in the field of physiology and cardiology. It is a method used to calculate cardiac output, the volume of blood being pumped by the heart, by measuring the amount of a certain substance being used by an organ or tissue.
Etymology
The principle is named after Adolf Fick, who first described the method in 1870. The term "Fick" is of German origin, and in this context, it refers to the surname of the scientist.
Definition
The Fick Principle states that the blood flow to an organ can be calculated using a marker substance if the following information is known: the amount of the substance taken up by the organ per unit time, the concentration of the substance in the blood supplying the organ, and the concentration of the substance in the blood leaving the organ.
Formula
The Fick Principle is usually expressed in the following formula:
CO = VO2 / (CaO2 - CvO2)
where:
- CO is the cardiac output
- VO2 is the rate of oxygen consumption
- CaO2 is the arterial oxygen content
- CvO2 is the venous oxygen content
Related Terms
- Cardiac Output: The volume of blood being pumped by the heart, usually in a one-minute period.
- Arterial Oxygen Content: The amount of oxygen in the arterial blood.
- Venous Oxygen Content: The amount of oxygen in the venous blood.
- Oxygen Consumption: The amount of oxygen a person uses in one minute.
See Also
External links
- Medical encyclopedia article on Fick principle
- Wikipedia's article - Fick principle
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