Fetal hydantoin syndrome
Fetal Hydantoin Syndrome
Fetal hydantoin syndrome (pronunciation: fee-tal hy-dan-toin sin-drome) is a disorder that occurs in infants and children as a result of maternal use of the medication phenytoin (pronunciation: fen-i-toin) to control seizures during pregnancy.
Etymology
The term "hydantoin" in fetal hydantoin syndrome is derived from the chemical structure of phenytoin, which is a hydantoin-derivative anticonvulsant. The term "fetal" refers to the fetus, the developing offspring in the uterus.
Symptoms
The syndrome is characterized by a pattern of minor anomalies and growth deficiencies, including craniofacial abnormalities, prenatal and postnatal growth retardation, and central nervous system (CNS) dysfunction.
Related Terms
- Phenytoin: An anticonvulsant drug that can be used to control seizures. It is the medication responsible for causing fetal hydantoin syndrome when used during pregnancy.
- Anticonvulsant: A group of pharmaceuticals used in the treatment of epileptic seizures.
- Craniofacial: Pertaining to the cranium and the face.
- Central Nervous System (CNS): The part of the nervous system consisting of the brain and spinal cord.
See Also
- Teratogen: Any agent that can disturb the development of an embryo or fetus.
- Fetal Alcohol Syndrome: A condition in a child that results from alcohol exposure during the mother's pregnancy.
References
- Jones KL, Smith DW. Recognition of the fetal alcohol syndrome in early infancy. Lancet. 1973 Nov 3;2(7836):999-1001.
- Hanson JW, Smith DW. The fetal hydantoin syndrome. J Pediatr. 1975 Nov;87(2):285-90.
External links
- Medical encyclopedia article on Fetal hydantoin syndrome
- Wikipedia's article - Fetal hydantoin syndrome
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