Factor x deficiency

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Factor X Deficiency

Factor X deficiency (pronounced: "Factor Ten Deficiency") is a rare bleeding disorder that is caused by a deficiency in a protein in the blood known as Factor X. This protein plays a crucial role in the coagulation cascade, which is the process that leads to the formation of blood clots.

Etymology

The term "Factor X" comes from the Roman numeral for 10, as it was the tenth clotting factor to be discovered. The term "deficiency" refers to the lack or shortage of something.

Causes

Factor X deficiency is usually inherited, which means it is passed down through families. It is caused by a mutation in the F10 gene, which provides instructions for making Factor X. This condition is inherited in an autosomal recessive manner, meaning both copies of the gene in each cell have mutations.

Symptoms

Symptoms of Factor X deficiency can vary widely, from mild to severe. They may include easy bruising, prolonged bleeding from minor wounds, nosebleeds, bleeding gums, blood in the urine (hematuria), and in women, heavy menstrual periods (menorrhagia).

Diagnosis

Diagnosis of Factor X deficiency typically involves blood tests to measure the amount of Factor X in the blood and to assess the overall ability of the blood to clot. Genetic testing may also be performed to identify mutations in the F10 gene.

Treatment

Treatment for Factor X deficiency typically involves replacing the missing Factor X through infusions of plasma or a plasma-derived Factor X concentrate. In some cases, antifibrinolytic medications may be used to help prevent or control bleeding.

Related Terms

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