Factor v
Factor V
Factor V (pronounced as "factor five") is a protein of the coagulation system, usually existing in an inactive form, which is transformed into active form (Factor Va) during the process of blood clotting.
Etymology
The term "Factor V" is derived from the Latin word "factor" meaning "maker" and the Roman numeral "V" for 5. It was discovered in the mid-20th century during a series of experiments on blood clotting.
Function
Factor V is essential for the conversion of prothrombin to thrombin, which in turn plays a crucial role in blood clotting. It acts as a cofactor for Factor X in the prothrombinase complex.
Related Terms
- Factor V Leiden: A mutation of Factor V gene leading to a hypercoagulable state.
- Prothrombin: An important protein in the coagulation system that Factor V helps convert into thrombin.
- Thrombin: An enzyme that converts fibrinogen to fibrin during blood clotting.
- Fibrin: A fibrous protein involved in the clotting of blood.
- Coagulation: The process by which blood changes from a liquid to a gel, forming a clot.
See Also
External links
- Medical encyclopedia article on Factor v
- Wikipedia's article - Factor v
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