Factor
Factor V Leiden
Factor V Leiden (pronounced: "Factor Five Leyden") is a mutation of one of the clotting factors in the blood called factor V. This particular mutation can increase your chance of developing abnormal blood clotting (thrombophilia).
Etymology
The term "Factor V Leiden" is named after the city of Leiden in the Netherlands, where the mutation was first identified in 1994.
Related Terms
- Thrombophilia: A condition in which there is an increased tendency for excessive blood clotting.
- Factor V: One of the substances that the body uses to help blood clot.
- Mutation: A change in the DNA sequence of a gene.
- Blood Clot: A clump of blood that has changed from a liquid to a gel-like or semisolid state.
Symptoms
People with Factor V Leiden may not have any symptoms until they form a clot. When clots do form, they can lead to various symptoms depending on where the clot is located. These can include Deep vein thrombosis (DVT), Pulmonary embolism (PE), and in rare cases, Stroke.
Diagnosis
Diagnosis of Factor V Leiden involves blood tests that can detect the presence of the Factor V Leiden mutation. These tests are usually only performed if a person has a personal or family history of abnormal blood clotting.
Treatment
Treatment for Factor V Leiden is focused on preventing abnormal blood clots and treating them if they do occur. This can involve the use of anticoagulant medications, lifestyle changes, and in some cases, surgical procedures.
See Also
External links
- Medical encyclopedia article on Factor
- Wikipedia's article - Factor
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