Ezogabine
Ezogabine
Ezogabine (pronunciation: /ˌɛzoʊˈɡæbiːn/), also known as retigabine in Europe, is an anticonvulsant medication used primarily in the treatment of epilepsy. It is a potassium channel opener that stabilizes the electrical activity in the brain, which aids in preventing seizure activity.
Etymology
The name "Ezogabine" is derived from the chemical name of the drug, which is N-(2-amino-4-(4-fluorobenzylamino)-phenyl)carbamic acid ethyl ester. The name "retigabine" is used in Europe and is derived from the chemical structure of the drug, which contains a retingabine moiety.
Usage
Ezogabine is used in combination with other medications to treat partial-onset seizures in adults. It is not used as a first-line treatment, but rather is used when other treatments have not been effective. The exact way that ezogabine works is not known, but it is believed to reduce the activity of nerve cells in the brain that cause seizures.
Side Effects
Common side effects of ezogabine include dizziness, fatigue, confusion, problems with coordination, and blurred vision. More serious side effects can include changes in mood or behavior, hallucinations, and difficulty urinating.
Related Terms
- Anticonvulsant: A type of medication used to prevent seizures.
- Epilepsy: A neurological disorder characterized by recurrent seizures.
- Seizure: A sudden, uncontrolled electrical disturbance in the brain.
External links
- Medical encyclopedia article on Ezogabine
- Wikipedia's article - Ezogabine
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