Exudate

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Exudate

Exudate (/ɛksjʊdeɪt/) is a fluid rich in protein and cellular elements that oozes out of blood vessels due to inflammation and is deposited in nearby tissues. The process of exudation is a result of increased vessel permeability, which is caused by the action of inflammatory mediators such as histamine and bradykinin.

Etymology

The term "exudate" is derived from the Latin word "exsudare", which means "to sweat out". It was first used in the medical context in the mid-19th century.

Types of Exudate

There are several types of exudate, including:

  • Serous: This is a clear, watery fluid that is similar to blood serum. It is often seen in mild inflammation.
  • Fibrinous: This is a thick, sticky exudate with a high content of fibrinogen and fibrin. It is often seen in severe inflammation.
  • Purulent: Also known as pus, this exudate contains dead leukocytes, tissue debris, and bacteria. It is often seen in bacterial infections.
  • Hemorrhagic: This exudate contains red blood cells and is often seen in severe tissue injury.

Related Terms

  • Transudate: This is a fluid that passes through a membrane or tissue, typically as a result of increased hydrostatic pressure or decreased osmotic pressure. Unlike exudate, transudate is low in protein and cellular elements.
  • Inflammation: This is a protective response of the body to injury or infection, characterized by redness, heat, swelling, and pain. Exudate is often produced during inflammation.
  • Edema: This is a condition characterized by an excess of watery fluid collecting in the cavities or tissues of the body. Both exudate and transudate can contribute to edema.

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