Extractable nuclear antigen

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Extractable Nuclear Antigen (ENA)

Extractable Nuclear Antigen (pronunciation: ex-trac-table nu-clear an-ti-gen) is a group of autoantibodies that are directed against certain proteins found in the nucleus of a cell. They are often associated with specific autoimmune diseases and are used as markers to help diagnose and manage these conditions.

Etymology

The term "Extractable Nuclear Antigen" is derived from its function and location. "Extractable" refers to the ability to isolate these antigens from the cell nucleus, "Nuclear" indicates their location within the nucleus of the cell, and "Antigen" is a substance that triggers an immune response, in this case, the production of autoantibodies.

Related Terms

  • Autoantibodies: These are antibodies that are directed against an individual's own proteins. They play a significant role in autoimmune diseases.
  • Autoimmune diseases: These are conditions where the immune system mistakenly attacks the body's own cells.
  • Antigen: This is a substance that triggers an immune response, especially the production of antibodies.
  • Nucleus (cell): This is the central part of a cell that houses the cell's genetic material.
  • Protein: Proteins are large, complex molecules that play many critical roles in the body. They are required for the structure, function, and regulation of the body's tissues and organs.

See Also

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