Drug interaction
Drug interaction
Drug interaction (/drʌɡ ɪntərˈækʃən/) refers to the phenomenon where a drug's effects are altered by the presence of another drug, food, drink, or some environmental chemical agents.
Etymology
The term "drug interaction" is derived from the English words "drug" (from Old French "drogue", possibly from Middle Dutch "droge-vate", meaning "dry barrels", referring to medicinal plants preserved in them) and "interaction" (from Latin "inter-", meaning "between" and "actio", meaning "a doing or a making").
Types of Drug Interactions
Drug interactions can be broadly classified into two types:
- Pharmacodynamic interaction: This occurs when two drugs interact in the body and cause an effect that is greater than the sum of their individual effects.
- Pharmacokinetic interaction: This occurs when one drug affects the absorption, distribution, metabolism, or excretion of another drug, thereby altering its concentration in the body.
Related Terms
- Synergism: This is a type of drug interaction where the effect of two drugs combined is greater than the sum of their individual effects.
- Antagonism: This is a type of drug interaction where one drug reduces or cancels out the effect of another drug.
- Potentiation: This is a type of drug interaction where one drug enhances the effect of another drug.
- Drug incompatibility: This is a situation where two drugs cannot be mixed together without altering the effectiveness or safety of either drug.
See Also
External links
- Medical encyclopedia article on Drug interaction
- Wikipedia's article - Drug interaction
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