Drug-induced keratoderma

Drug-induced keratoderma (pronunciation: /drʌg ɪnˈdjuːst kɛrəˈtɔːdərmə/) is a medical condition characterized by the thickening of the skin on the palms of the hands and soles of the feet, caused by certain medications.

Etymology

The term "keratoderma" is derived from the Greek words "keras" (horn) and "derma" (skin), indicating a condition of horn-like skin. The prefix "drug-induced" specifies that the condition is caused by the intake of certain drugs.

Causes

Drug-induced keratoderma is caused by the intake of certain medications. These can include retinoids, cytotoxic drugs, and antiretroviral drugs. The exact mechanism by which these drugs cause keratoderma is not fully understood, but it is believed to involve the disruption of normal skin cell growth and differentiation.

Symptoms

The primary symptom of drug-induced keratoderma is the thickening of the skin on the palms and soles. This can be accompanied by other symptoms such as redness, scaling, and pain. The severity of symptoms can vary depending on the specific drug and the individual's response to it.

Treatment

Treatment for drug-induced keratoderma primarily involves discontinuing the offending drug, if possible. Other treatments can include the use of emollients, keratolytics, and, in severe cases, systemic retinoids.

Related Terms

• Keratoderma
• Palmoplantar keratoderma
• Drug-induced skin disorders

External links

• Medical encyclopedia article on Drug-induced keratoderma
• Wikipedia's article - Drug-induced keratoderma

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