Dronedarone
Dronedarone
Dronedarone (pronounced: droh-NEH-dah-rone) is a medication used to treat atrial fibrillation and atrial flutter. It is classified as a Class III antiarrhythmic agent.
Etymology
The name "Dronedarone" is derived from the drug's chemical structure, which is similar to that of Amiodarone, with the key difference being the absence of the iodine moiety present in Amiodarone. The prefix "drone-" is a reference to this structural difference.
Usage
Dronedarone is used to reduce the risk of hospitalization in patients with paroxysmal or persistent atrial fibrillation or atrial flutter. It is not recommended for use in patients with unstable hemodynamics or severe heart failure.
Mechanism of Action
Dronedarone works by inhibiting multiple ion channels in the heart, which helps to slow the heart rate and restore a regular rhythm. It also has anti-adrenergic activity, which further contributes to its antiarrhythmic effects.
Side Effects
Common side effects of Dronedarone include nausea, diarrhea, abdominal pain, and vomiting. Serious side effects can include liver damage, lung disease, and heart failure.
Related Terms
External links
- Medical encyclopedia article on Dronedarone
- Wikipedia's article - Dronedarone
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