Dose-dependent
Dose-dependent
Dose-dependent (pronunciation: /doʊs-dɪˈpɛndənt/) is a term used in pharmacology and toxicology to describe the change in effect on the body in relation to the amount of a drug or toxin administered.
Etymology
The term is derived from the English words "dose," which refers to a quantity of a medicine or drug taken or recommended to be taken at a particular time, and "dependent," which means contingent on or determined by.
Definition
In a dose-dependent relationship, the effect of a drug increases or decreases as the dose increases or decreases. This relationship can be linear or non-linear, depending on the drug or toxin in question.
Related Terms
- Pharmacodynamics: The study of the biochemical and physiological effects of drugs and their mechanisms of action.
- Pharmacokinetics: The study of how the body absorbs, distributes, metabolizes, and excretes drugs.
- Therapeutic index: The ratio of the dose of a drug that causes a harmful effect to the dose that causes a therapeutic effect.
- Toxicity: The degree to which a substance can harm humans or animals.
See Also
External links
- Medical encyclopedia article on Dose-dependent
- Wikipedia's article - Dose-dependent
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