Dexfenfluramine
Dexfenfluramine
Dexfenfluramine (pronounced: dex-fen-flu-ra-meen) is a serotoninergic anorectic drug that was marketed under the brand name Redux by Interneuron Pharmaceuticals. It was used as an appetite suppressant in the treatment of obesity before being voluntarily withdrawn from the market due to concerns about potential heart valve damage.
Etymology
The term "Dexfenfluramine" is derived from the chemical name for the compound, which is (+)-fenfluramine. The "dex" prefix refers to the dextrorotatory isomer of fenfluramine, which is the active component of the drug.
Usage
Dexfenfluramine was used as a short-term supplement to diet and exercise in the treatment of obesity. It worked by decreasing appetite, which led to a reduction in caloric intake and subsequent weight loss. However, its use was associated with an increased risk of pulmonary hypertension and heart valve disease, which led to its withdrawal from the market.
Related Terms
- Anorectic: A drug that suppresses appetite.
- Serotoninergic: Pertaining to neurons that produce or are affected by serotonin.
- Obesity: A medical condition characterized by excess body fat.
- Pulmonary Hypertension: High blood pressure that affects the arteries in the lungs and the right side of the heart.
- Interneuron Pharmaceuticals: A pharmaceutical company that marketed Dexfenfluramine under the brand name Redux.
See Also
- Fenfluramine: A drug that was used as an appetite suppressant, which is chemically related to Dexfenfluramine.
- Phentermine: A medication used together with diet and exercise to treat obesity.
External links
- Medical encyclopedia article on Dexfenfluramine
- Wikipedia's article - Dexfenfluramine
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