Desmoplastic fibroma

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Desmoplastic Fibroma

Desmoplastic fibroma (pronunciation: des-mo-plas-tic fi-bro-ma) is a rare, benign, locally aggressive tumor that typically affects the bones and soft tissues.

Etymology

The term "desmoplastic" is derived from the Greek words "desmos" which means "band" or "bond", and "plastikos" which means "molded". "Fibroma" is derived from the Latin word "fibra" meaning "fiber" and the Greek suffix "-oma" meaning "tumor". Thus, "desmoplastic fibroma" can be interpreted as a tumor molded by fibrous bands.

Definition

A desmoplastic fibroma is a non-cancerous growth that primarily affects the bones, particularly the mandible and long bones. It is characterized by the proliferation of well-differentiated fibroblasts within a dense collagenous stroma. Despite being benign, it can be locally aggressive and cause significant morbidity due to its potential to invade surrounding tissues and cause bone destruction.

Symptoms

Symptoms of desmoplastic fibroma may include pain, swelling, and functional impairment of the affected area. In some cases, pathological fractures may occur due to the weakening of the bone structure.

Diagnosis

Diagnosis of desmoplastic fibroma is typically made through a combination of radiographic imaging and histopathological examination. The tumor often presents as a lytic, well-defined, non-calcified mass on radiographs. Histologically, it is characterized by a proliferation of fibroblasts within a dense collagenous stroma.

Treatment

Treatment options for desmoplastic fibroma include surgical resection, radiotherapy, and in some cases, chemotherapy. The choice of treatment depends on the size and location of the tumor, as well as the patient's overall health status.

Related Terms

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