Dermal equivalent
Dermal Equivalent
Dermal Equivalent (pronunciation: der-mal ek-wuh-vuh-luhnt) is a term used in the field of Dermatology and Tissue Engineering to describe a laboratory-grown substitute for the dermis layer of the skin.
Etymology
The term "Dermal Equivalent" is derived from the words "dermal", referring to the dermis or the thick layer of living tissue below the Epidermis that forms the true skin, containing blood capillaries, nerve endings, sweat glands, hair follicles, and other structures, and "equivalent", meaning equal in value, amount, function, or meaning.
Definition
A Dermal Equivalent is a bioengineered skin substitute that mimics the structure and function of the native dermis. It is typically composed of a Collagen matrix populated with Fibroblasts, which are cells that produce collagen and other fibers. Dermal Equivalents are used in the treatment of various skin conditions, including burns, chronic wounds, and in reconstructive surgery.
Related Terms
- Dermis: The thick layer of living tissue below the epidermis that forms the true skin, containing blood capillaries, nerve endings, sweat glands, hair follicles, and other structures.
- Epidermis: The outermost layer of the skin, providing a waterproof barrier and creating our skin tone.
- Collagen: The most abundant protein in the body, it is the substance that holds the body together. It is found in the bones, muscles, skin, and tendons.
- Fibroblasts: A type of cell that synthesizes the extracellular matrix and collagen, the structural framework for animal tissues, and plays a critical role in wound healing.
External links
- Medical encyclopedia article on Dermal equivalent
- Wikipedia's article - Dermal equivalent
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