Dense deposit disease
Dense Deposit Disease (pronounced: denz deh-poh-zit dih-zeez), also known as DDD, is a rare disease that affects the kidneys. It is a type of glomerulonephritis, which is a group of diseases that cause inflammation and damage to the kidney's filtering units.
Etymology
The term "Dense Deposit Disease" is derived from the characteristic dense deposits that are seen in the glomerular basement membrane (GBM) when examined under an electron microscope.
Symptoms
The symptoms of Dense Deposit Disease can vary greatly from person to person. Some people may have no symptoms at all, while others may experience symptoms such as blood in the urine (hematuria), protein in the urine (proteinuria), and swelling (edema). In severe cases, Dense Deposit Disease can lead to kidney failure.
Causes
Dense Deposit Disease is caused by a problem with the body's immune system. Specifically, it is associated with abnormalities in the complement system, a part of the immune system that helps the body fight off infections.
Diagnosis
Diagnosis of Dense Deposit Disease is typically made through a kidney biopsy, which involves taking a small sample of kidney tissue for examination under a microscope. The dense deposits in the GBM can be seen using special staining techniques.
Treatment
There is currently no cure for Dense Deposit Disease. Treatment is aimed at managing symptoms and slowing the progression of the disease. This may include medications to control blood pressure, reduce proteinuria, and suppress the immune system. In some cases, plasma exchange or kidney transplantation may be considered.
See also
External links
- Medical encyclopedia article on Dense deposit disease
- Wikipedia's article - Dense deposit disease
This WikiMD dictionary article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski