Demecolcine
Demecolcine
Demecolcine (pronounced as de-me-col-cine) is a pharmaceutical drug used in the treatment of various medical conditions.
Etymology
The term "Demecolcine" is derived from the Greek words "deme," meaning "to build," and "colcine," a reference to the Colchicum autumnale plant from which the drug is derived.
Definition
Demecolcine is a chemotherapeutic agent that is used primarily in the treatment of cancer. It is a derivative of the naturally occurring alkaloid, colchicine, and works by inhibiting microtubule polymerization, which disrupts the mitotic spindle, and thus, cell division.
Usage
Demecolcine is used in the treatment of various types of cancer, including leukemia, lymphoma, and solid tumors. It is also used in cytogenetics to arrest cell division at metaphase for chromosome analysis.
Related Terms
- Colchicine: A naturally occurring alkaloid from which demecolcine is derived.
- Mitosis: The process of cell division that demecolcine disrupts.
- Microtubule: A component of the cell's cytoskeleton that is targeted by demecolcine.
- Chemotherapy: The use of drugs like demecolcine to treat diseases such as cancer.
See Also
External links
- Medical encyclopedia article on Demecolcine
- Wikipedia's article - Demecolcine
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