DNA probe
DNA Probe
A DNA probe (pronounced: /diː.eɪnˈəʊb/) is a strand of DNA that is labeled with a radioactive or fluorescent molecule and used to detect the presence of a complementary sequence by hybridization.
Etymology
The term "DNA probe" is derived from the acronym DNA, which stands for Deoxyribonucleic acid, and the word "probe", which in this context means to investigate or examine.
Definition
A DNA probe is a fragment of DNA that is used in genetic testing to detect the presence of DNA sequences that are associated with a particular trait or disease. The probe is designed to bind, or hybridize, to a specific sequence of DNA in a sample. If the sequence is present, the probe will bind to it and produce a signal that can be detected.
Usage
DNA probes are used in a variety of applications, including genetic testing, forensic science, and research. They are particularly useful in the detection of genetic disorders, as they can identify specific mutations in a person's DNA that are associated with a particular disease.
Related Terms
- Hybridization: The process by which a DNA probe binds to a specific sequence of DNA in a sample.
- Genetic Testing: The use of DNA probes and other techniques to test for the presence of genetic disorders.
- Forensic Science: The application of DNA probes and other scientific techniques to the investigation of crime.
- Research: The use of DNA probes in scientific studies to investigate the function of genes and the role of DNA in disease.
External links
- Medical encyclopedia article on DNA probe
- Wikipedia's article - DNA probe
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