Cyclizine

From WikiMD
Jump to navigation Jump to search

Information about Cyclizine

Cyclizine and chlorcyclizine are first generation antihistamines that are used largely to treat or prevent motion sickness and nausea.

Liver safety of Cyclizine

Cyclizine has been linked to very rare instances of clinically apparent acute liver injury.

Mechanism of action of Cyclizine

Cyclizine (sye' kli zeen) and chlorcyclizine (klor sye' kli zeen) are first generation antihistamines and antiemetics that belong to the piperazine class of these agents (with hydroxyzine and meclizine). Cyclizine and chlorcyclizine are most commonly used to treat the symptoms of nausea, vomiting and dizziness associated with motion sickness. However, they are also used to review symptoms of allergic rhinitis and the common cold, particularly in combination with sympathomimetic agents such as phenylephrine.

FDA approval information for Cyclizine

Cyclizine was first approved for use in the United States in 1966. It is still widely used and is available as tablets or capsules of 25 mg in multiple generic forms and under the trade name Cyclivert and Bonine in both prescription and nonprescription forms.

Dosage and administration for Cyclizine

The typical dose is 1 or 2 tablets one hour before travel. Chlorcyclizine is used in a similar dose regimen. Both cyclizine and chlorcyclizine are also available as chewable tablets and in oral liquid formulations as well as combinations with sympathomimetic agents (pseudoephedrine) for the treatment of symptoms of the common cold and nasal congestion.

Side effects of Cyclizine

Common side effects include sedation, impairment of motor function, confusion, dizziness, blurred vision, dry mouth and throat, palpitations, tachycardia, abdominal distress, constipation and headache. Antihistamines can worsen urinary retention and glaucoma.

First Generation Antihistamines

Second Generation Antihistamines

Cost and Coupons - Cyclizine

Reviews for Cyclizine

This article is a stub. YOU can help Wikimd by expanding it!

Articles on Cyclizine

Wikipedia

Learn more about Cyclizine

Help WikiMD

Find something you can improve? Join WikiMD as an an editor and help improve this page or others.

Apple bitten.svg

WikiMD is a free medical encyclopedia and wellnesspedia moderated by medical professionals.

W8MD weight loss logo

Ad. Tired of being overweight?. W8MD's insurance Weight loss program can HELP*

Quick links: Medicine Portal | Encyclopedia‏‎‏‎ | Gray's Anatomy‏‎ | Topics‏‎ |‏‎ Diseases‏‎ | Drugs | Wellness | Obesity‏‎ | Metabolic syndrome | Weight loss*
Disclaimer: The entire contents of WIKIMD.ORG are for informational purposes only and do not render medical advice or professional services. If you have a medical emergency, you should CALL 911 immediately! Given the nature of the wiki, the information provided may not be accurate, misleading and or incorrect. Use the information on this wiki at your own risk! See full Disclaimer.
Link to this page: <a href="http://www.wikimd.org/wiki/Cyclizine">Cyclizine</a>

  • Individual results may vary for weight loss from our sponsors.