Cutaneous mastocytosis

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Cutaneous Mastocytosis (pronounced: kyu-tay-nee-us mas-to-sy-toh-sis) is a medical condition characterized by an abnormal accumulation of mast cells in the skin. The term is derived from the Greek words "kutis" meaning skin, and "mastos" meaning breast, and "cytosis" from the Greek "kytos" meaning container or cell, referring to an increase in the number of cells.

Definition

Cutaneous Mastocytosis is a form of Mastocytosis, a group of rare disorders caused by an overproduction of mast cells in the body. In the case of Cutaneous Mastocytosis, these excess mast cells accumulate in the skin, leading to various skin lesions and symptoms.

Symptoms

The most common symptoms of Cutaneous Mastocytosis include urticaria pigmentosa, a skin condition characterized by brownish lesions that may blister or itch, and Darier's sign, a wheal and flare reaction that occurs when the skin is lightly stroked.

Causes

The exact cause of Cutaneous Mastocytosis is unknown, but it is believed to be due to a mutation in the KIT gene, which is involved in the growth and development of mast cells.

Diagnosis

Diagnosis of Cutaneous Mastocytosis is typically made through a skin biopsy, where a small sample of skin is removed and examined under a microscope for the presence of an increased number of mast cells.

Treatment

Treatment for Cutaneous Mastocytosis is primarily aimed at managing symptoms and may include antihistamines to reduce itching, corticosteroids to reduce inflammation, and light therapy (phototherapy) to improve the appearance of skin lesions.

See Also

External links

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