Contig
Contig
Contig (/ˈkɒntɪɡ/), derived from the term "contiguous", is a term used in genomics and bioinformatics to refer to an overlapping sequence of DNA or RNA.
Pronunciation
- IPA: /ˈkɒntɪɡ/
Etymology
The term "contig" is derived from the English word "contiguous", which means "touching or connected throughout in an unbroken sequence". In the context of genomics and bioinformatics, it refers to sequences of DNA or RNA that are assembled by overlapping the ends of shorter sequences.
Definition
In genomics and bioinformatics, a contig is a set of overlapping DNA segments that together represent a consensus region of DNA. In the context of genomics, contigs are used to provide a physical map of a chromosome or a genome. They are the result of successful sequence assembly.
Related Terms
- Sequence assembly: The process of taking a large number of short DNA sequences and putting them back together to create a representation of the original chromosomes from which the DNA originated.
- Genome: The complete set of genes or genetic material present in a cell or organism.
- Chromosome: A thread-like structure of nucleic acids and protein found in the nucleus of most living cells, carrying genetic information in the form of genes.
- Bioinformatics: An interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex.
- Genomics: The study of the genomes of organisms. The field includes intensive efforts to determine the entire DNA sequence of organisms and fine-scale genetic mapping.
External links
- Medical encyclopedia article on Contig
- Wikipedia's article - Contig
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