Conn syndrome

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Conn Syndrome

Conn syndrome (pronounced: /kɒn/), also known as primary hyperaldosteronism or primary aldosteronism, is a hormonal disorder that involves an overproduction of the hormone aldosterone by the adrenal glands. This condition was first described by Jerome W. Conn in 1955, hence the name.

Etymology

The term "Conn syndrome" is derived from the name of the American endocrinologist Jerome W. Conn who first described the condition. The term "hyperaldosteronism" comes from the Greek words "hyper" meaning "over", "aldo" referring to the hormone aldosterone, and "ism" denoting a condition or disease.

Symptoms

The symptoms of Conn syndrome can vary, but often include high blood pressure (hypertension), muscle weakness, excessive thirst (polydipsia), excessive urination (polyuria), and a low level of potassium in the blood (hypokalemia).

Causes

Conn syndrome is most commonly caused by a benign tumor of the adrenal gland (adenoma). Less commonly, it can be caused by an overgrowth of both adrenal glands (hyperplasia).

Diagnosis

Diagnosis of Conn syndrome typically involves blood tests to measure levels of aldosterone and renin, a hormone that regulates blood pressure. Imaging tests such as CT scans or MRI may also be used to identify any abnormalities in the adrenal glands.

Treatment

Treatment for Conn syndrome usually involves surgery to remove the adrenal gland if an adenoma is present. Medications may also be used to block the effects of aldosterone.

Related Terms

See Also

External links

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