Ciclosporin
Ciclosporin
Ciclosporin (pronounced: /ˌsɪkləˈspɔːrɪn/), also spelled Cyclosporine and Cyclosporin, is a type of immunosuppressant medication. It is used to prevent the body from rejecting a transplanted organ, such as a kidney, heart, or liver. It is also used to treat certain autoimmune diseases.
Etymology
The term "Ciclosporin" is derived from the fungus Tolypocladium inflatum from which it was first isolated. The fungus was found in a soil sample in Norway in 1969. The name "Ciclosporin" comes from the circular (cyclo-) shape of the spores (-sporin) of the fungus.
Usage
Ciclosporin works by suppressing the activity of certain cells in the immune system that can attack the transplanted organ or the body's own tissues in autoimmune diseases. It is usually taken orally, but can also be given by injection in severe cases.
Related Terms
- Immunosuppressant: A type of drug that reduces the body's immune response, preventing it from attacking its own tissues or a transplanted organ.
- Autoimmune disease: A condition in which the immune system mistakenly attacks the body's own tissues.
- Transplant rejection: A process in which the immune system attacks a transplanted organ, leading to its failure.
Side Effects
Like all medications, Ciclosporin can cause side effects. These can include kidney damage, high blood pressure, liver problems, and an increased risk of infections due to the suppression of the immune system.
See Also
External links
- Medical encyclopedia article on Ciclosporin
- Wikipedia's article - Ciclosporin
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