Cetrorelix
Cetrorelix
Cetrorelix (/sɛˈtrɔːrɪlɛks/) is a synthetic decapeptide with potent gonadotropin-releasing hormone (GnRH) antagonist properties. It is primarily used in assisted reproduction to control ovulation.
Etymology
The name "Cetrorelix" is derived from the chemical structure of the drug. "Cetro" is a prefix used in chemistry to denote a compound with four substituents, referring to the four amino acids in the peptide chain of Cetrorelix. "Relix" is a suffix used in pharmacology to denote a drug that acts as a receptor antagonist, indicating the drug's mechanism of action.
Usage
Cetrorelix is used in assisted reproductive technologies (ART) to prevent premature ovulation in women undergoing controlled ovarian hyperstimulation. It allows for the timing of the final maturation of the eggs and their subsequent collection for in-vitro fertilization (IVF).
Mechanism of Action
Cetrorelix works by blocking the action of gonadotropin-releasing hormone (GnRH) on the pituitary gland. This prevents the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), thereby inhibiting ovulation.
Related Terms
- Gonadotropin-Releasing Hormone (GnRH)
- Luteinizing Hormone (LH)
- Follicle-Stimulating Hormone (FSH)
- Assisted Reproductive Technology (ART)
- In-Vitro Fertilization (IVF)
External links
- Medical encyclopedia article on Cetrorelix
- Wikipedia's article - Cetrorelix
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