Cell line

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Cell line

A Cell line (/sɛl laɪn/) is a permanently established cell culture that propagates indefinitely given appropriate fresh medium and space.

Etymology

The term "Cell line" is derived from the English words "cell", which comes from the Latin cella meaning a small room, and "line", which comes from the Old English line meaning a cord or thread.

Definition

Cell lines are derived from a single cell and therefore consist of cells with a uniform genetic makeup. They are used extensively in biological research and biotechnology, including virology, pharmacology, and genetics.

Types of Cell Lines

There are two types of cell lines, primary cell line and continuous cell line. Primary cell lines are established from tissue explants or cell suspensions and have a limited lifespan. Continuous cell lines, on the other hand, are immortal and can be propagated indefinitely.

Related Terms

  • Cell Culture: The process by which cells are grown under controlled conditions.
  • Primary Cell Line: A cell line that has a limited lifespan and cannot be propagated indefinitely.
  • Continuous Cell Line: A cell line that is immortal and can be propagated indefinitely.
  • Virology: The study of viruses and virus-like agents.
  • Pharmacology: The study of drug action.
  • Genetics: The study of genes, genetic variation, and heredity in living organisms.

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