Cefpiramide

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Cefpiramide

Cefpiramide (pronounced: sef-pi-ram-ide) is a third-generation cephalosporin antibiotic used in the treatment of various bacterial infections.

Etymology

The term "Cefpiramide" is derived from the parent class of antibiotics it belongs to, known as cephalosporins. The "-piramide" suffix is unique to this particular drug and does not have a known etymology.

Usage

Cefpiramide is primarily used to treat severe infections caused by bacteria that are resistant to other antibiotics. It is particularly effective against Gram-negative bacteria, including Pseudomonas aeruginosa and Enterobacteriaceae.

Mechanism of Action

Cefpiramide works by inhibiting the synthesis of the bacterial cell wall, leading to cell death. It binds to penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, inhibiting the cross-linking of peptidoglycan chains necessary for bacterial cell wall strength and rigidity.

Side Effects

Common side effects of Cefpiramide include nausea, vomiting, diarrhea, and rash. In rare cases, it can cause serious side effects such as Clostridium difficile-associated diarrhea (CDAD), Stevens-Johnson syndrome, and anaphylaxis.

Related Terms

  • Cephalosporin: The class of antibiotics that Cefpiramide belongs to.
  • Antibiotic: A type of antimicrobial substance active against bacteria.
  • Gram-negative bacteria: A group of bacteria that do not retain the crystal violet stain used in the gram-staining method of bacterial differentiation.

External links

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