Caseous necrosis

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Caseous Necrosis

Caseous necrosis (pronunciation: kay-see-us ne-kro-sis) is a form of cell death in which the tissue maintains a cheese-like appearance. The term is derived from the Latin word "caseus" meaning cheese. It is characteristic of tuberculosis, but can also be seen in other conditions.

Definition

Caseous necrosis is a distinctive form of coagulative necrosis, is encountered most often in tuberculosis. Caseous necrosis is a form of cell death in which the tissue maintains a cheese-like appearance.

Etymology

The term "caseous" is derived from the Latin "caseus" which means cheese, referring to the cheese-like appearance of the necrotic tissue. The term "necrosis" is derived from the Greek "nekros" which means dead body or corpse.

Pathology

In caseous necrosis, the dead cells disintegrate but are not completely digested, leaving behind granular, clumped material. This material has a soft, crumbly texture and a pale, yellowish color, similar to certain types of cheese, hence the name.

Clinical Significance

Caseous necrosis is most commonly associated with tuberculosis, but it can also occur in other conditions such as syphilis, certain fungal infections, and lymphoma. The presence of caseous necrosis in a biopsy sample can be a useful diagnostic clue in these conditions.

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