Cascara
Information about Cascara
Cascara is a popular herbal medication and over-the-counter therapy of constipation.
Liver safety of Cascara
Cascara is generally safe and well tolerated, but can cause adverse events including clinically apparent liver injury when used in high doses for longer than recommended periods.
Mechanism of action of Cascara
Cascara sagrada is an herbal medication used for centuries as a laxative which is now available in the United States without prescription for short term treatment of constipation. Cascara is typically an extract from the dried, aged bark of Rhamnus purshiana, a species of buckthorn tree or shrub native to North America.
History of Cascara
Cascara sagrada is Spanish for “sacred bark” and was used for centuries by Native Americans as a laxative. Cascara became accepted in western medical practice in the 19th century and is still used in over-the-counter laxative preparations, often in combination with other herbals such as aloe vera. The active laxative components in cascara are anthraquinone derivatives and their glucosides, referred to as cascarosides. They appear to act locally as an irritant to the colon promoting peristalsis and stool evacuation. Anthraquinones also inhibit reabsorption of electrolytes and water from the colon. Cascara is minimally absorbed.
Dosage and administration for Cascara
The typical dose is 300 mg once daily, but it is recommended for short term use only (less than one week). Side effects include abdominal cramps and electrolyte imbalance. Long term use or abuse can lead to “cathartic” colon with diarrhea, cramps, weight loss and darkened pigmentation of the colonic mucosa.
Herbal and dietary supplements
- Aloe Vera, Ashwagandha, Astragalus, Bilberry, Black Cohosh, Butterbur, Cat's Claw, Cascara, Chaparral, Comfrey, Crofelemer, Echinacea, Ephedra, Fenugreek, Flavocoxid, Garcinia cambogia, Germander, Ginkgo, Ginseng, Greater Celandine, Green Tea, Hoodia, Hops, Horse Chestnut, Hyssop, Kava Kava, Kratom, Lavender, Maca, Margosa Oil, Melatonin, Milk Thistle, Noni, Passionflower, Pennyroyal Oil, Red Yeast Rice, Resveratrol, Saw Palmetto, Senna, Skullcap, Spirulina, St. John's Wort, Turmeric, Usnic Acid, Valerian, Yohimbine
Chinese and Other Asian Herbal Medicines
- Ba Jiao Lian, Bol Gol Zhee, Chi R Yun, Jin Bu Huan, Ma Huang, Sho Saiko To and Dai Saiko To, Shou Wu Pian
Multi-Ingredient Nutritional Supplements
See also Nutritional supplements
Cost and Coupons - Cascara
- GoodRx compare cost & coupons for Cascara
- Find the lowest cost of Cascara
- Search for Coupons for Cascara
Reviews for Cascara
Articles on Cascara
This article is a stub. YOU can help Wikimd by expanding it!
Learn more about Cascara
|
|
|
|
|
- According to Peter Frishauf, founder of Medscape, wiki is the future of medicine!
- Knowledge is power. Let us empower the people! Join WikiMD and be an editor.
 Ad. Tired of being overweight?. W8MD's insurance weight loss can HELP* |
Disclaimer: The entire contents of WIKIMD.ORG are for informational purposes only and do not render medical advice or professional services. If you have a medical emergency, you should CALL 911 immediately! Given the nature of the wiki, the information provided may not be accurate, misleading and or incorrect. Use the information on this wiki at your own risk! See full Disclaimer. * Individual results may vary for weight loss from our sponsors.
Our sponsors WikiMD is supported by W8MD weight loss, sleep and medical aesthetic centers.
