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Information about Carbinoxamine

Carbinoxamine is a first generation antihistamine that is used for symptoms of allergic rhinitis and the common cold.

Liver safety of Carbinoxamine

Carbinoxamine has not been linked to instances of clinically apparent acute liver injury.

Mechanism of action of Carbinoxamine

Carbinoxamine (kar" bin ox' a meen) is a first generation antihistamine that is used for alleviation of symptoms of allergic rhinitis and the common cold, including sneezing, cough, runny note, watery eyes and itching. Carbinoxamine also has mild anticholinergic effects. After reports of deaths in children less than 2 years of age who were taking carbinoxamine, its use has been restricted to adults and children over the age of 2.

Dosage and administration for Carbinoxamine

Carbinoxamine is currently available by prescription only in 4 mg tablets and as syrup (4 mg/5 mL) in several generic forms and under the brand name Palgic.

Dosage and administration for Carbinoxamine

The recommended adult oral dose is 4 to 8 mg one to four times daily.

Side effects of Carbinoxamine

Common side effects include sedation, impairment of motor function, confusion, dizziness, blurred vision, dry mouth and throat, palpitations, tachycardia, abdominal distress, constipation and headache. Antihistamines can worsen urinary retention and glaucoma.

First Generation Antihistamines

Second Generation Antihistamines

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