CTLA-4

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CTLA-4
TermCTLA-4
Short definitionCTLA-4 - A protein found on T cells (a type of immune cell) that helps keep the body's immune responses in check. When CTLA-4 is attached to another protein called B7, it helps keep T cells from killing other cells, including cancer cells. 
TypeCancer terms
SpecialtyOncology
LanguageEnglish
SourceNCI
Comments


CTLA-4 - A protein found on T cells (a type of immune cell) that helps keep the body's immune responses in check. When CTLA-4 is attached to another protein called B7, it helps keep T cells from killing other cells, including cancer cells. Some cancer drugs called immune checkpoint inhibitors are used to block CTLA-4. When this protein is blocked, the immune system's "brakes" are released and the ability of T cells to kill cancer cells is increased

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