CIOMS/RUCAM scale
CIOMS/RUCAM scale
The CIOMS/RUCAM scale (pronounced: "see-oms/roo-kam scale"), also known as the Roussel Uclaf Causality Assessment Method or Council for International Organizations of Medical Sciences scale, is a widely used tool for assessing the causality of adverse drug reactions (ADRs).
Etymology
The term "CIOMS" is an acronym for the Council for International Organizations of Medical Sciences, an international, non-governmental, non-profit organization established jointly by WHO and UNESCO in 1949. "RUCAM" stands for Roussel Uclaf Causality Assessment Method, named after the French pharmaceutical company Roussel Uclaf that developed this method.
Usage
The CIOMS/RUCAM scale is used to determine the likelihood that a drug caused a specific adverse event. It is a structured, standardized, validated, and hepatotoxicity-specific diagnostic tool that attributes scores to individual key items, such as the time from drug intake to the onset of the reaction, course of the reaction after stopping the drug, risk factors, concomitant drugs, and the response to unintentional re-exposure to the drug.
Related Terms
- Adverse drug reaction (ADR): Any unexpected, undesired, or excessive response to a drug.
- Hepatotoxicity: The capacity of a drug, chemical, or other exposure to produce injury to the liver.
- Pharmacovigilance: The science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems.
See Also
External links
- Medical encyclopedia article on CIOMS/RUCAM scale
- Wikipedia's article - CIOMS/RUCAM scale
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