Buccal swab

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Buccal Swab

A Buccal Swab (pronunciation: /ˈbʌkəl swɒb/) is a method used to collect DNA samples from the cells on the inside of a person's cheek. The term "buccal" is derived from the Latin word "bucca," which means cheek, while "swab" comes from the Middle English word "swabbe," meaning mop or sponge.

Procedure

The procedure involves using a small, soft brush or cotton swab to scrape the inside of the cheek. This is a non-invasive and painless method to collect DNA samples. The collected cells are then sent to a laboratory for DNA analysis.

Uses

Buccal swabs are commonly used in genetic testing, paternity testing, and in forensic investigations. They are also used in the field of epigenetics to study changes in gene expression or cellular phenotype.

Advantages and Disadvantages

The main advantage of a buccal swab is that it is a non-invasive and painless method of collecting DNA samples. It is also a quick and easy procedure that can be performed at home. However, the amount of DNA collected from a buccal swab is often less than that obtained from a blood sample. This can sometimes result in the need for repeat testing.

Related Terms

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