Biphenotypic sinonasal sarcoma

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Biphenotypic sinonasal sarcoma (pronunciation: bi-fee-no-typ-ik si-no-nay-zal sar-ko-ma) is a rare type of cancer that primarily affects the sinonasal region.

Etymology

The term "biphenotypic" is derived from the Greek words "bi" meaning two, and "phenotype" referring to the observable characteristics of an individual. "Sinonasal" refers to the region encompassing the sinuses and nasal cavity. "Sarcoma" is a term used for cancers that originate from connective tissues.

Definition

Biphenotypic sinonasal sarcoma is a distinctive, low-grade malignant neoplasm that arises in the sinonasal region. It is characterized by dual differentiation, with both myogenic and neural features.

Symptoms

Common symptoms of biphenotypic sinonasal sarcoma include nasal obstruction, recurrent sinusitis, and epistaxis (nosebleeds).

Diagnosis

Diagnosis of biphenotypic sinonasal sarcoma is typically made through a combination of clinical examination, imaging studies such as CT scan or MRI, and histopathological examination of a biopsy specimen.

Treatment

Treatment typically involves surgical resection, often followed by radiation therapy. The role of chemotherapy in the treatment of biphenotypic sinonasal sarcoma is currently unclear.

Prognosis

The prognosis for biphenotypic sinonasal sarcoma is generally favorable, with a low rate of distant metastasis. However, local recurrence is common, necessitating close follow-up.

Related Terms

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