Balsalazide
Balsalazide (pronunciation: bal-SAL-a-zide) is a prodrug that is used in the treatment of ulcerative colitis, a type of inflammatory bowel disease.
Etymology
The term "Balsalazide" is derived from its chemical structure, which consists of 5-aminosalicylic acid (5-ASA) linked to a 4-aminobenzoyl-beta-alanine molecule.
Pharmacology
Balsalazide is a prodrug that is metabolized in the colon into the active drug, 5-aminosalicylic acid. This drug works by reducing inflammation in the colon, which helps to alleviate the symptoms of ulcerative colitis.
Usage
Balsalazide is typically taken orally in the form of a capsule. The usual dosage is three capsules taken twice daily, for a total of six capsules per day. However, the exact dosage may vary depending on the patient's condition and response to treatment.
Side Effects
Common side effects of balsalazide include headache, abdominal pain, diarrhea, and nausea. In rare cases, it can cause serious side effects such as pancreatitis, blood disorders, and severe allergic reactions.
Related Terms
- 5-aminosalicylic acid
- Ulcerative colitis
- Inflammatory bowel disease
- Prodrug
- 4-aminobenzoyl-beta-alanine
See Also
External links
- Medical encyclopedia article on Balsalazide
- Wikipedia's article - Balsalazide
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