Azzopardi phenomenon

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Azzopardi Phenomenon

Azzopardi Phenomenon (pronunciation: az-zo-par-di phe-nom-e-non) is a medical term named after the Maltese pathologist Joseph G. Azzopardi, who first described it in 1959.

Etymology

The term 'Azzopardi Phenomenon' is derived from the name of the pathologist who first described this phenomenon, Joseph G. Azzopardi. The word 'phenomenon' comes from the Greek word 'phainomenon', which means 'thing appearing to view'.

Definition

The Azzopardi Phenomenon refers to the presence of necrotic tumor cells within blood vessels, particularly in cases of malignant melanoma and lung cancer. This phenomenon is characterized by the deposition of DNA from necrotic tumor cells on the walls of small blood vessels, leading to the formation of a glassy, eosinophilic hyaline material.

Related Terms

  • Necrosis: The death of cells or tissues from severe injury or disease, especially in a localized area of the body. Causes of necrosis include inadequate blood supply, bacterial infection, traumatic injury, and cancer.
  • Malignant Melanoma: A type of skin cancer that begins in cells known as melanocytes. While it is less common than other skin cancers, it is more dangerous because it is more likely to spread to other parts of the body if not caught early.
  • Lung Cancer: A type of cancer that begins in the lungs. It is one of the most common and deadly types of cancer.
  • DNA: Deoxyribonucleic acid, a self-replicating material present in nearly all living organisms as the main constituent of chromosomes. It is the carrier of genetic information.

See Also

External links

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