Azelastine

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Azelastine

Azelastine (pronounced as /æzɪˈlæstiːn/) is a potent, second-generation, selective, histamine antagonist (H1-receptor) used in the treatment of hay fever, rhinitis, and urticaria.

Etymology

The term "Azelastine" is derived from the parent compound phthalazinone, a heterocyclic compound that is a key component in its chemical structure.

Usage

Azelastine is primarily used as a nasal spray to treat symptoms of allergic rhinitis such as sneezing, itching, and runny or stuffy nose. It is also available as an ophthalmic solution for treating itchy eyes caused by allergies.

Mechanism of Action

Azelastine works by blocking the action of histamine, a substance in the body that causes allergic symptoms. It also has anti-inflammatory effects, reducing the swelling and irritation in the nasal passages.

Related Terms

  • Antihistamine: A type of medicine that blocks the effects of histamine, a chemical released by the body during an allergic reaction.
  • Histamine: A compound that is released by cells in response to injury and in allergic and inflammatory reactions, causing contraction of smooth muscle and dilation of capillaries.
  • Rhinitis: Inflammation of the mucous membrane of the nose, caused by a virus infection (e.g. the common cold) or by an allergic reaction (e.g. hay fever).
  • Urticaria: A rash of round, red welts on the skin that itch intensely, sometimes with dangerous swelling, caused by an allergic reaction, typically to specific foods.

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