Anticipation
Anticipation
Anticipation (/æntɪsɪˈpeɪʃən/) is a term used in various fields of medicine. It refers to the phenomenon where the symptoms of a genetic disorder become apparent at an earlier age as it is passed on to the next generation. In most cases, the severity of the symptoms increases with each successive generation.
Etymology
The term 'anticipation' comes from the Latin word 'anticipatio', which means 'taking before'. In the context of medicine, it refers to the early onset of symptoms in each successive generation.
Related Terms
- Genetic disorder: A disease caused by abnormalities in an individual's genome. Anticipation is often observed in certain genetic disorders.
- Symptom: A physical or mental feature which is regarded as indicating a condition of disease, particularly such a feature that is apparent to the patient.
- Generation: In medicine, generation often refers to the people living at the same time and who are roughly the same age.
- Genome: The complete set of genes or genetic material present in a cell or organism.
In Medicine
In the field of medicine, anticipation is a phenomenon that is often observed in various genetic disorders such as Huntington's disease, Myotonic dystrophy, and Fragile X syndrome. It is characterized by an increase in severity and decrease in the age of onset in successive generations. This is often due to an increase in the number of trinucleotide repeats in the gene responsible for the disorder.
Anticipation is a key factor to consider in genetic counseling. It helps in predicting the likelihood of a genetic disorder being passed on to the next generation and the potential severity of the symptoms.
External links
- Medical encyclopedia article on Anticipation
- Wikipedia's article - Anticipation
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