Antagomir

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Antagomir

Antagomir (pronunciation: an-tag-o-mir) is a type of oligonucleotide that is chemically engineered to silence certain microRNA molecules in the body.

Etymology

The term "Antagomir" is derived from the words "antagonist" and "miR", a common abbreviation for microRNA. The term was first coined by researchers at the Rockefeller University in 2005.

Function

Antagomirs function by binding to specific microRNAs and preventing them from interacting with their target mRNA molecules. This can effectively silence the microRNA, preventing it from carrying out its normal function in the cell. This has potential applications in the treatment of various diseases, including cancer, cardiovascular disease, and neurodegenerative disorders.

Related Terms

  • Oligonucleotide: A short DNA or RNA molecule that is used in genetic testing, research, and forensics.
  • MicroRNA: A small non-coding RNA molecule that functions in RNA silencing and post-transcriptional regulation of gene expression.
  • mRNA: Messenger RNA, a type of RNA molecule that conveys genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.

See Also

External links

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