Amonafide

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Amonafide

Amonafide (pronunciation: /a-mo-na-fide/) is a chemotherapeutic agent that is primarily used in the treatment of cancer. It belongs to the class of antineoplastic agents known as DNA intercalators.

Etymology

The term "Amonafide" is derived from the chemical name Acridine-mononaphthalene-fide. The suffix "-fide" is a common ending for drugs that intercalate with DNA.

Mechanism of Action

Amonafide works by intercalating into the DNA of cancer cells, disrupting their growth and division. This leads to cell death and the reduction of the cancerous mass. It is particularly effective against leukemia and lymphoma.

Side Effects

Like many chemotherapeutic agents, Amonafide can have severe side effects. These can include nausea, vomiting, hair loss, and myelosuppression. It is important for patients to discuss these potential side effects with their healthcare provider before starting treatment.

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