Aminoglycoside
Aminoglycoside
Aminoglycoside (pronunciation: /ˌæmɪnoʊˈɡlaɪkəˌsaɪd/) is a class of antibiotics used primarily to treat bacterial infections that are resistant to other antibiotics.
Etymology
The term "aminoglycoside" is derived from the chemical structure of these antibiotics, which contain an amino (nitrogen-containing) group and a glycoside (sugar-containing) group.
Usage
Aminoglycosides work by binding to the bacterial ribosome, inhibiting protein synthesis and causing misreading of the mRNA code, leading to cell death. They are particularly effective against aerobic, gram-negative bacteria.
Related Terms
Side Effects
Common side effects of aminoglycosides include ototoxicity (damage to the ear, potentially causing deafness) and nephrotoxicity (damage to the kidneys).
Resistance
Resistance to aminoglycosides can occur through various mechanisms, including modification of the antibiotic, alteration of the target site, or changes in membrane permeability.
External links
- Medical encyclopedia article on Aminoglycoside
- Wikipedia's article - Aminoglycoside
This WikiMD dictionary article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski