Aminoglutethimide
Aminoglutethimide
Aminoglutethimide (pronounced: a-mi-no-glu-te-thi-mide) is a medication primarily used in the treatment of Cushing's syndrome and metastatic breast cancer. It is an aromatase inhibitor, which means it works by reducing the production of estrogen in the body.
Etymology
The term "Aminoglutethimide" is derived from its chemical structure, which consists of an amino group (-NH2) and a glutethimide group (a five-membered ring with two carbonyl groups).
Usage
Aminoglutethimide is used in the treatment of Cushing's syndrome, a condition caused by an excess of the hormone cortisol. It is also used in the treatment of metastatic breast cancer, particularly in postmenopausal women. The drug works by inhibiting the enzyme aromatase, which is involved in the production of estrogen.
Related Terms
- Cushing's syndrome: A condition caused by an excess of the hormone cortisol.
- Breast cancer: A type of cancer that forms in the cells of the breasts.
- Aromatase inhibitor: A class of drugs that reduce the production of estrogen in the body.
- Estrogen: A group of hormones that play an important role in the normal sexual and reproductive development in women.
Side Effects
Common side effects of Aminoglutethimide include dizziness, skin rash, and nausea. More serious side effects can include liver damage and blood disorders.
See Also
External links
- Medical encyclopedia article on Aminoglutethimide
- Wikipedia's article - Aminoglutethimide
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