Aminocandin

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Aminocandin

Aminocandin (/ˌæmɪnoʊˈkændɪn/) is a class of antifungal drugs that inhibit the synthesis of beta-glucan, a major component of the cell wall in many fungi.

Etymology

The term "aminocandin" is derived from the words "amino," referring to the presence of an amino group, and "candin," a suffix used in the names of several antifungal drugs.

Pharmacology

Aminocandins work by inhibiting the enzyme 1,3-beta-D-glucan synthase, which is responsible for the production of beta-glucan in the fungal cell wall. This results in a weakened cell wall and ultimately leads to the death of the fungus.

Related Terms

  • Antifungal: A type of medication used to treat fungal infections.
  • Beta-glucan: A type of polysaccharide that is a major component of the cell wall in many fungi.
  • 1,3-beta-D-glucan synthase: An enzyme responsible for the production of beta-glucan in the fungal cell wall.
  • Amino group: A functional group that consists of a nitrogen atom attached by single bonds to hydrogen atoms.

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